Chapter: Modern Medical Toxicology: Corrosive(Caustic) Poisons: Alkalis and Other Caustics
Cetrimide - Corrosive(Caustic) Poisons
Cetrimide (atrimonium bromide) is a quaternary ammonium compound.
Cetrimide
Cetrimide (atrimonium bromide) is a
quaternary ammonium compound. It is commonly used as a disinfectant. Common
Indian preparations of cetrimide include Cetavlon
(20% solu-tion), Cetrilak (5%
solution), and Savlon (15% solution
with 7.5% chlorhexidine*).
Ingestion of cetrimide causes gastrointestinal irritation
with vomiting. Systemic effects include a curare-like paralysis (because of
depolarising neuromuscular blocking action), CNS depression, hypotension, and
respiratory failure.
Usual
fatal dose is said to be about 3 grams.
Treatment
is the same as for all caustics. Administration of soap solution orally as a
first-aid measure may help inactivate its toxic effect.
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Modern Medical Toxicology: Corrosive(Caustic) Poisons: Alkalis and Other Caustics : Cetrimide - Corrosive(Caustic) Poisons |
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Modern Medical Toxicology: Corrosive(Caustic) Poisons: Alkalis and Other Caustics