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Chapter: Modern Medical Toxicology: Corrosive(Caustic) Poisons: Alkalis and Other Caustics

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Cetrimide - Corrosive(Caustic) Poisons

Cetrimide (atrimonium bromide) is a quaternary ammonium compound.

Cetrimide

Cetrimide (atrimonium bromide) is a quaternary ammonium compound. It is commonly used as a disinfectant. Common Indian preparations of cetrimide include Cetavlon (20% solu-tion), Cetrilak (5% solution), and Savlon (15% solution with 7.5% chlorhexidine*).Ingestion of cetrimide causes gastrointestinal irritation with vomiting. Systemic effects include a curare-like paralysis (because of depolarising neuromuscular blocking action), CNS depression, hypotension, and respiratory failure.

Usual fatal dose is said to be about 3 grams.

Treatment is the same as for all caustics. Administration of soap solution orally as a first-aid measure may help inactivate its toxic effect.

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