YERSINIA PESTIS
BACTERIOLOGY
Y. pestis is a nonmotile, non–spore-forming,
Gram-negative bacillus with a tendency to- ward pleomorphism and bipolar
staining. It is a member of the Enterobacteriaceae and is discussed with other
members of the genus Yersinia. It
shares features of the other Yersinia
pathogenic for humans (Y.
pseudotuberculosis, Y. enterocolitica), such as virulence plasmids and Yersinia outer membrane proteins (Yops).
In addition, Y. pestis has two
additional virulence plasmids, which code for a protein capsular antigen called
F1 and enzymes with phospholipase, protease, and fibrinolytic activity. Y. pestis also has its own adhesin
similar to the invasins of the other Yersinia.
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