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Chapter: Clinical Cases in Anesthesia : Congenital Diaphragmatic Hernia

What is permissive hypercapnia?

Permissive hypercapnia was recently introduced as an alternative modality in the treatment of neonates with CDH.

What is permissive hypercapnia?

 

Permissive hypercapnia was recently introduced as an alternative modality in the treatment of neonates with CDH. Conventional ventilatory management resulted in baro-trauma to the lungs secondary to the high pressures needed to achieve adequate ventilation and oxygenation. In permis-sive hypercapnia, the arterial carbon dioxide tension (PaCO2) is allowed to rise while maintaining adequate oxygenation and acid-base balance. The goal is to maintain a preductal oxygen saturation of greater than 90%. Acid-base balance is maintained with either bicarbonate or tris(hydroxymethyl) aminomethane (THAM).



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Clinical Cases in Anesthesia : Congenital Diaphragmatic Hernia : What is permissive hypercapnia? |


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