Chapter: Clinical Cases in Anesthesia : Congenital Diaphragmatic Hernia
What is permissive hypercapnia?
Permissive hypercapnia was recently introduced as an alternative modality in the treatment of neonates with CDH.
What is permissive hypercapnia?
Permissive hypercapnia was recently introduced
as an alternative modality in the treatment of neonates with CDH. Conventional
ventilatory management resulted in baro-trauma to the lungs secondary to the
high pressures needed to achieve adequate ventilation and oxygenation. In
permis-sive hypercapnia, the arterial carbon dioxide tension (PaCO2)
is allowed to rise while maintaining adequate oxygenation and acid-base
balance. The goal is to maintain a preductal oxygen saturation of greater than
90%. Acid-base balance is maintained with either bicarbonate or
tris(hydroxymethyl) aminomethane (THAM).
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Clinical Cases in Anesthesia : Congenital Diaphragmatic Hernia : What is permissive hypercapnia? |
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Clinical Cases in Anesthesia : Congenital Diaphragmatic Hernia