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Chapter: Modern Medical Toxicology: Neurotoxic Poisons: Anticonvulsants and Antiparkinsonian Drugs

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Trihexiphenidyl - Antiparkinsonian Drug

It is also referred to as benzhexol hydrochloride and is used in the treatment of Parkinsonism, extrapyramidal syndromes, and nerve gas poisoning.

Trihexiphenidyl

It is also referred to as benzhexol hydrochloride and is used in the treatment of Parkinsonism, extrapyramidal syndromes, and nerve gas poisoning. Trihexiphenidyl is a synthetic tertiary amine antimuscarinic agent.

Chronic use results in memory and cognitive impairments. Sudden withdrawal can cause anxiety, irritability, insomnia, headache, sweating, and tachycardia.

Overdose causes anticholinergic manifestations such as confusion, hallucinations, dry mouth, dilated pupils, diplopia, achycardia, and hyperthermia.

Treatment involves supportive measures, and continuous ECG and cardiac monitoring,

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