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In addition to challenges related to ambivalence about stopping opioid use, patients often have serious problems with nonopioid substance abuse and/or with medical, psychiatric, legal, employ-ment and family/social issues that preexist or result from the addiction. Research has found that addressing these additional problems can be helpful, but is complex and requires coordina-tion between agonist pharmacotherapy staff, and other medical and psychosocial services.
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