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Chapter: Obstetrics and Gynecology: Neoplasia Gestational Trophoblastic

Placental Site Tumors

Placental site tumor is a rare form of trophoblastic disease.

PLACENTAL SITE TUMORS

 

Placental site tumor is a rare form of trophoblastic disease. The tumor is comprised of monomorphic populations of intermediate cytotrophoblastic cells that are locally inva-sive at the site of placental implantation. The tumor only secretes small amounts of hCG, and can be better fol-lowed by human placental lactogen levels. This tumor is rarely metastatic and is much more resistant to standard chemotherapy. Hysterectomy as initial therapy is often curative

 

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