NMDA Receptors
NMDA receptors are broadly and unevenly distributed
across the mammalian CNS.
In addition to reports that NMDA antagonists are
anx-iolytic, there is a body of preclinical literature indicating that NMDA
receptor activation is anxiogenic.
These studies are reminiscent of, and in some sense parallel, studies with
benzodi-azepine receptor inverse agonists
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