Hyperbaric Oxygen Therapy
The intense oxidizing properties of high-pressure oxygen (hyperbaric oxygen) can have valuable
therapeutic effects in several important clinical conditions. Therefore, large
pressure tanks are now available in many medical centers into which patients
can be placed and treated with hyperbaric oxygen. The oxygen is usually
administered at PO2s of 2 to 3 atmospheres of pressure through a mask or intra-tracheal
tube, whereas the gas around the body is normal air compressed to the same
high-pressure level.
It is believed that the same oxidizing free radicals responsible
for oxygen toxicity are also responsible for at least some of the therapeutic
benefits. Some of the conditions in which hyperbaric oxygen therapy has been
especially beneficial follow.
Probably the most successful use of hyperbaric oxygen has been for
treatment of gas gangrene. The
bacteria that cause this condition, clostridial
organ-isms, grow best under anaerobic conditions andstop growing at oxygen
pressures greater than about 70 mm Hg. Therefore, hyperbaric oxygenation of the
tissues can frequently stop the infectious process entirely and thus convert a
condition that formerly was almost 100 per cent fatal into one that is cured in
most instances by early treatment with hyperbaric therapy.
Other conditions in which hyperbaric oxygen therapy has been either
valuable or possibly valuable include decompression sickness, arterial gas
embolism, carbon monoxide poisoning, osteomyelitis, and myocardial infarction.
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