ASSAY METHODS
A good number of pharmaceutical substances can be assayed
gravimetrically. The gravimetric meth-ods adopted vary according to the nature
of the substance under determination. However, most of the sub-stances being
estimated gravimetrically fall into one or the other categories stated below,
which would be discussed briefly with suitable examples :
(a) Substances
assayed gravimetrically,
(b) Substances
assayed after conversion :
(i) Substances
assayed after conversion to Free Acid,
(ii) Substances
assayed after conversion to Free Base,
(iii)
Substances assayed after conversion to Free Compound, and
(iv) Substances
assayed after conversion to Derivatives or Substitution Products.
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