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Chapter: Medicine Study Notes : Evidence Based Medicine

Evaluation of Therapy

Assessment of an article about Therapy

Evaluation of Therapy

 

Assessment of an article about Therapy

 

·        Are the results of the study valid?

o   Was the assignment of patients to treatments randomised? 

o   Was follow-up complete? (Non-follow-ups may have died, etc ® bias)

o   Were patients analysed in the groups to which they were randomised?

o   Were patients and researchers „blind‟ to the treatment

o   Were the groups similar at the start of the trial

o   Other than the intervention, were the groups treated equally?

·        What were the results?

o   How large was the treatment effect? RR, RRR, ARR 

o   How precise was the estimate of the treatment effect? Point estimate & Confidence intervals. What is the P value?

·        Will the results help me in caring for my patients?

o   Can the results be applied to my patient care?

·        Were all clinically important outcomes considered: were the outcomes relevant for the patient? Or was only a benefit to intermediate outcomes considered?

·        Do treatment benefits out-weight harms and costs?  ARR and NNT/NNH

 

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Medicine Study Notes : Evidence Based Medicine : Evaluation of Therapy |


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