Doxepin

DOXEPIN

The tricyclic tertiary amine doxepin (Zonalon, Prudox), a potent H₁- and H₂-receptor antagonist, is indicated for the short-term relief of pruritus associated with topical eczematous dermatitis. Systemic absorption occurs, and the drug may potentiate or alter the metabolism of a variety of other systemic agents. Drowsiness is the most common adverse side effect.