ANTIHISTAMINES
A large number of oral H1-receptor
antagonists are available with and
without prescription for the treatment of mast cell–mediated diseases, such as
acute and chronic urticaria, angioedema, and cutaneous mastocytosis. Until
relatively recently, two major limita-tions of the available antihistamines,
such as diphenhy-dramine (Benadryl),
hydroxyzine (Atarax), prometh-azine (Phenergan), and cyproheptadine (Periactin), were their short half-lives
and sedative effects. New-genera-tion long-acting antihistamines pass the
blood-brain bar-rier much less readily and are theoretically less likely to
cause somnolence. Examples of these relatively nonse-dating drugs are
fexofenadine (Allegra), cetirizine (Zyrtec), and loratadine (Claritin).
Related Topics
Privacy Policy, Terms and Conditions, DMCA Policy and Compliant
Copyright © 2018-2023 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.