Chapter: 12th Microbiology : Chapter 3 : Control of Microorganisms by Chemical Methods

Difference between Bactericidal and Bacteriostatic

Difference between and comparison of Bactericidal and Bacteriostatic

• Bactericidal refers to agents that kill bacteria

• Action is irreversible

• Inhibit the cell wall formation of bacteria

• Do not work with the immune system of the host

• Minimal Bactericidal Concentration (MBC) refers to the concentration of the drug required to kill 99.99% of the bacterial population

• Examples include betalactam antibiot- ics, cephalosporins, and vancomycin

• Bacteriostatic refers to agents that prevent the growth of bacteria

• Action is reversible

• Inhibit DNA replication and protein synthesis of bacteria

• Work with the immune system of the host to prevent the growth and reproduction of bacteria

• Minimal Inhibitory Concentration (MIC) is the minimum drug concentration which inhibits the bacterial growth

• Examples include tetracyclines, spectinomycin, chloramphenicol, sulfonamides, etc.

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12th Microbiology : Chapter 3 : Control of Microorganisms by Chemical Methods : Difference between Bactericidal and Bacteriostatic |