Pseudoallescheria boydii Infection
Pseudoallescheria boydii is a mold that causes an
opportunisticinfection in immunocompromised persons, such as patients with HIV.
It causes a disease, which clinically resembles aspergillosis. The diagnosis is
made by demonstration of sep-tate hyphae in tissue that resemble with those of Aspergillus. It can be differentiated
from Aspergillus by culture on SDA
medium. On culture, P. boydii
produces pear-shaped conidia. The fungus causes cutaneous zygomycosis and
disseminated zygomycosis. Ketoconazole and itraconazole are the drugs of choice for treatment of P. boydii infection. Amphotericin B is not useful. Surgical removal
of necrotic infected tissue is also useful.
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