Pseudoallescheria boydii Infection
Pseudoallescheria boydii is a mold that causes an opportunisticinfection in immunocompromised persons, such as patients with HIV. It causes a disease, which clinically resembles aspergillosis. The diagnosis is made by demonstration of sep-tate hyphae in tissue that resemble with those of Aspergillus. It can be differentiated from Aspergillus by culture on SDA medium. On culture, P. boydii produces pear-shaped conidia. The fungus causes cutaneous zygomycosis and disseminated zygomycosis. Ketoconazole and itraconazole are the drugs of choice for treatment of P. boydii infection. Amphotericin B is not useful. Surgical removal of necrotic infected tissue is also useful.