The polyomaviruses include the JC virus (JCV) and BK virus (BKV) of humans and simian virus 40 (SV40) of monkeys. Polyomaviruses, like papillomaviruses, are members of the papovavirus family. They are also double-stranded, naked capsid DNA viruses and are widely distributed among various animal species, usually without causing apparent disease. However, they are able to transform cells of a variety of heterologous cell lines in culture.
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