Pantothenic acid mainly is incorporated in the body into coenzyme A (CoA), which has many metabolic roles inthe cells.
Deficiency of pantothenic acid in lower animals can cause retarded growth, failure of reproduction, graying of the hair, dermatitis, fatty liver, and hemorrhagic adrenocortical necrosis. In the human being, no definite deficiency syndrome has been proved, presumably because of the wide occurrence of this vitamin in almost all foods and because small amounts can probably be synthesized in the body. This does not mean that pan-tothenic acid is not of value in the metabolic systems of the body; indeed, it is perhaps as necessary as any other vitamin.
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