Levorphanol
Levorphanol (Levo-Dromoran) is an L-isomer morphi-nan derivative
of morphine that is five to seven times more potent than morphine. It produces
all of the side effects associated with morphine but less nausea. It is
indicated for moderate to severe pain as a preoperative anxiolytic. It is often
used in combination with thiopen-tal to reduce the latter drug’s anesthetic
dose and to de-crease postoperative recovery time. The D-isomer of levorphanol,
dextrorphan, does not possess opioid anal-gesic activity but is a useful
antitussive.
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