Kaolin and pectin
pectin mixtures are locally acting OTC antidiarrheals.They work by
adsorbing irritants and soothing the intestinal mu-cosa.
Kaolin and pectin aren’t absorbed and, therefore,
aren’t distrib-uted throughout the body. They’re excreted in stool.
Kaolin and pectin act as adsorbents, binding with
bacteria, toxins, and other irritants in the intestinal mucosa. Pectin
decreases the pH in the intestinal lumen and provides a soothing effect on the
Kaolin and pectin are used to relieve mild to
moderate acute diar-rhea. They may also be used to temporarily relieve chronic
diar-rhea until the cause is determined and definitive treatment begun.
These antidiarrheals can interfere with the
absorption of digoxin and other drugs by the intestinal mucosa if administered
at the same time. (See Adverse reactions
to kaolin and pectin.)