Antiflatulents disperse gas pockets in the GI tract. They’re
avail-able alone or in combination with antacids. A major antiflatulent drug
currently in use is simethicone.
Antiflatulents aren’t absorbed from the GI tract.
They’re distrib-uted only in the intestinal lumen and are eliminated intact in
Antiflatulents provide defoaming action in the GI
tract. By produc-ing a film in the intestines, simethicone disperses
mucus-enclosed gas pockets and helps prevent their formation.
Antiflatulents are prescribed to treat conditions
in which excess gas is a problem, such as:
functional gastric bloating
postoperative gaseous bloating
spastic or irritable colon
Simethicone doesn’t interact significantly with
other drugs and doesn’t cause known adverse reactions.