Chapter: Modern Medical Toxicology: Neurotoxic Poisons: Hallucinogens (Psychedelic Drugs)

Dimethyltryptamine (DMT) - Hallucinogen(Psychedelic Drug)

N,N- Dimethyltryptamine (DMT) is a hallucinogen obtained from the seeds and leaves of certain South American plants such as Piptadenia pergyina and Virola calophylla, as well as in the tropical legume Mucuna pruriens.

DIMETHYLTRYPTAMINE (DMT)

N,N- Dimethyltryptamine (DMT) is a hallucinogen obtained from the seeds and leaves of certain South American plants such as Piptadenia pergyina and Virola calophylla, as well as in the tropical legume Mucuna pruriens.

Dimethltryptamine (DMT) is not absorbed from the gastro-intestinal tract, and so is typically snorted, smoked, or injected. This elicits a virtually instantaneous onset of visual hallucina-tions, bodily dissociation, extreme shifts in mood, and auditory phenomena. Effects peak within 2 minutes after injection, and resolve in 20 to 30 minutes. This has earned it the name “busi-nessman’s trip”. Physical effects include mydriasis, raised body temperature, tachycaria and hypertension.

Treatment involves “talking the patient down” in a quiet, dark room, and institution of symptomatic measures. Phenothiazines should be avoided to minimise the danger of convulsions.

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Modern Medical Toxicology: Neurotoxic Poisons: Hallucinogens (Psychedelic Drugs) : Dimethyltryptamine (DMT) - Hallucinogen(Psychedelic Drug) |