Home | | Medical Physiology | Differences Between the Myenteric and Submucosal Plexuses

Chapter: Medical Physiology: General Principles of Gastrointestinal Function- Motility, Nervous Control, and Blood Circulation

| Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail |

Differences Between the Myenteric and Submucosal Plexuses

The myenteric plexus consists mostly of a linear chain of many interconnecting neurons that extends the entire length of the gastrointestinal tract.

Differences Between the Myenteric and Submucosal Plexuses

The myenteric plexus consists mostly of a linear chain of many interconnecting neurons that extends the entire length of the gastrointestinal tract. A section of this chain is shown in Figure 62–4.

Because the myenteric plexus extends all the way along the intestinal wall and because it lies between the longitudinal and circular layers of intestinal smooth muscle, it is concerned mainly with controlling muscle activity along the length of the gut. When this plexus is stimulated, its principal effects are (1) increased tonic contraction, or “tone,” of the gut wall, increased intensity of the rhythmical contractions, slightly increased rate of the rhythm of contraction, and (4) increased velocity of conduction of excitatory waves along the gut wall, causing more rapid move-ment of the gut peristaltic waves.


The myenteric plexus should not be considered entirely excitatory because some of its neurons are inhibitory; their fiber endings secrete an inhibitorytransmitter, possibly vasoactive intestinal polypeptide or some other inhibitory peptide. The resulting inhibitory signals are especially useful for inhibiting some of the intestinal sphincter muscles that impede movement of food along successive segments of the gastrointestinal tract, such as the pyloric sphincter, which controls emptying of the stomach into the duo-denum, and the sphincter of the ileocecal valve, which controls emptying from the small intestine into the cecum.

The submucosal plexus, in contrast to the myenteric plexus, is mainly concerned with controlling function within the inner wall of each minute segment of the intestine. For instance, many sensory signals originate from the gastrointestinal epithelium and are then integrated in the submucosal plexus to help control local intestinal secretion, local absorption, and local contraction of the submucosal muscle that causesvarious degrees of infolding of the gastrointestinal mucosa.


Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail


Copyright © 2018-2020 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.