Chapter: Microbiology and Immunology: Immunodeficiency

Complement Deficiencies

Liver failure, Malnutrition.

Complement Deficiencies

◗ Liver failure

The synthesis of complement proteins is very much reduced in chronic hepatitis B or C and in liver failure caused by alcoholic cirrhosis. Hence, these patients are highly susceptible to infection by pyogenic bacteria.

◗ Malnutrition

In severe malnutrition, the synthesis of complement proteins by liver is reduced due to low supply of amino acids. Therefore, people with malnutrition are susceptible to infection by pyo-genic bacteria.

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Microbiology and Immunology: Immunodeficiency : Complement Deficiencies |