Home | | Medical Microbiology | Borrelia Burgdorferi - Bacteriology

Chapter: Medical Microbiology: An Introduction to Infectious Diseases: Spirochetes

| Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail |

Borrelia Burgdorferi - Bacteriology

B. burgdorferi is microaerophilic andcanbe grown with some difficulty in a specialized artificial culture medium.

BORRELIA BURGDORFERI

BACTERIOLOGY

B. burgdorferi is microaerophilic andcanbe grown with some difficulty in a specialized artificial  culture  medium.  The  doubling  time  under  these  conditions  is  long  (8  to 24 hours), so growth for isolation takes many days to weeks. B.burgdorferi consists of at least 10 different subspecies (eg, B.burgdorferi sensu stricto, B. afzelii,B.garini), which differ in geographic distribution and some clinical manifestations. All will be referred to as B.burgdorferi here. As with  other species of Borrelia, there  are  multiple  classes of OMPs, many  of which  undergo antigenic variation.  Recent studies have  focused  on a class called outer surface proteins (Osps), which have been linked to aspects of pathogen- esis and immunity. Two of these, OspA and OspC, are differentially expressed depending on the stage of tick or mammalian infection.


Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail


Copyright © 2018-2020 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.