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Chapter: Clinical Cases in Anesthesia : Coronary Artery Bypass Grafting

What are the major determinants of myocardial oxygen supply and demand?

The major determinants of myocardial oxygen supply include:

What are the major determinants of myocardial oxygen supply and demand?

 

The major determinants of myocardial oxygen supply include:

 

·  Coronary anatomy

·  Diastolic filling time

·  Aortic diastolic pressure (ADP)

·  Left ventricular end-diastolic  pressure (LVEDP)

·  Coronary perfusion pressure (CPP).

 

CPP = ADP – LVEDP

 

The major determinants of myocardial oxygen demand in decreasing order include:

 

·  Left ventricular wall tension

 

Tension = (pressure × radius)/2 × wall thickness

 

·  Heart rate

·  Contractility

·  Afterload.

 

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Clinical Cases in Anesthesia : Coronary Artery Bypass Grafting : What are the major determinants of myocardial oxygen supply and demand? |


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