Sickle Cell (Disease Anaemia in
Pregnancy)
Sickle
cell disorders are found most commonly in people of African or west Indian
origin.
In this
condition defective gene produce abnormal haemoglobin beta chains: the
resulting Hb is Hb SS.
Sickle Cell Anaemia: Sickle cells
have an increased fragility andshortened life span of 17 days resulting in
chronic haemolytic anaemia and causing episodes of ischaemia and pain; these
are known as sickle cell crisis. Women with sickle cell anaemia may be
subfertile but those who do become pregnant may already have organ damages.
Psychological
stress, cold climate, extreme temperature changes, smoking , induced hypoxia,
strenuous physical exercise, fatigue, respiratory disease and pregnancy.
Jaundice,
Anaemia, fatigue, joints pain, epigastric pain, vomiting, abdominal tension,
splenomegally, hepatomegally, pyrexia.
·
Risk of early abortion
·
premature birth
·
Intra uterine death
·
Low immunity.
·
Risk of embolism
·
Refer to bigger hospital with better equipments for
care
·
Regular monitoring of haemoglobin level
·
Anti-malaria therapy
·
Folate supplements
·
Blood transfusion every 6 weeks if necessary.
·
Advise woman to avoid situation that will
precipitate a crisis.
·
If crisis occurs, admit patient, rehydrate, treat
infection, relief pain, give oxygen therapy and blood transfusion.
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