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Chapter: Microbiology and Immunology: Virology, Virus: Rhabdoviruses

Laboratory Diagnosis in Humans - Rabies Virus Infection

Saliva, serum, cerebrospinal fluid (CSF), blood, urine, and skin and brain biopsy are the frequently used specimens for diagnosis of rabies.

Laboratory Diagnosis in Humans

 Specimens

Saliva, serum, cerebrospinal fluid (CSF), blood, urine, and skin and brain biopsy are the frequently used specimens for diagnosis of rabies.

 Microscopy

Demonstration of Negri bodies by microscopy is the character-istic histopathological feature of rabies (Fig. 64-3, Color Photo 59). Impression smears of the human brain tissue collected at postmortem are stained by Seller’s technique for demonstra-tion of Negri bodies. The stain contains methylene blue alcohol as fixative and basic fuchsin as staining reagent.



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Microbiology and Immunology: Virology, Virus: Rhabdoviruses : Laboratory Diagnosis in Humans - Rabies Virus Infection |


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