An uncommon condition in which there is death of fat cells within the breast.
The aetiology is unclear, it is suggested that the death of fat cells may result from trauma. There is an acute inflammatory response, which in some cases progresses to chronic inflammation and organisation with fibrous tissue. The result may be a hard, irregular mass, which can mimic carcinoma.
Patients present with a hard mass, which may also have skin tethering; often in an obese patient with large breasts. Although the patient may recall trauma, this is not helpful in diagnosis, as many cases of breast carcinoma are discovered after incidental trauma.
Plasma cells predominate. Lipidladen macrophages (foam cells/lipophages) may form multinucleate giant cells.
As for breast lump, using a triple assessment to exclude malignancy.