Adenovirus infections are found worldwide.
More than one serotypes of virus may produce the same clinical syndrome, and one serotype of virus may cause clinically dif-ferent diseases. Adenoviruses 1–7 are the common serotypes worldwide and are responsible for most cases of adenovirus-associated infections.
Adenovirus infections are exclusively human infections. No animal reservoirs are present. Infected symptomatic as well as asymptomatic humans who excrete adenoviruses intermit-tently in their respiratory secretions and also in their stool are the sources of infection. The infection is transmitted from person-to-person directly by
· aerosol droplets,
· feco–oral route,
· direct inoculation of conjunctiva by contaminated fingers,
· contaminated fomites including towels and medical instru-ments, and
· swimming in improperly disinfected swimming pool.
Overcrowding, poor hygiene, and close contact facilitate trans-mission of infection. Adenovirus typically affects children, starting from infants to school-going ones, though children of any age may be affected.