BACTEROIDES FRAGILIS
BACTERIOLOGY
The B. fragilis
group constitute the most common opportunistic pathogens of the genus Bacteroides. These
slim, pale-staining, capsulate,
Gram-negative rods form
colonies overnight on blood agar medium. The implication of fragility in
the name is misleading, because they are actually among the hardier and more
easily grown anaerobes. Most strains produce superoxide dismutase and are
relatively tolerant to atmospheric oxygen. B.
fragilis has surface pili and a capsule composed of a polymer of two
polysaccharides. The LPS endotoxin in the B.
fragilis outer membrane is less toxic than that of most other Gram-negative
bacteria, possibly due to modification or absence of the lipid A portion.
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