Antihypertensive drugs
Antihypertensive drugs, which act to reduce blood pressure, areused
to treat hypertension, a disorder characterized by elevation in systolic blood
pressure, diastolic blood pressure, or both.
Treatment for hypertension typically begins with a thiazide diuret-ic or
a calcium channel blocker. (For more information, see “Cal-cium channel
blockers,”) The patient may also receive a beta-adrenergic antagonist,
angiotensin-converting enzyme (ACE) inhibitor, or an angiotensin II receptor
blocker. The choice of these drugs depends on whether the patient has a
compelling indi-cation, such as heart failure, history of an MI, high risk of
coro-nary artery disease (CAD), diabetes, or chronic kidney disease. (See
“Beta-adrenergic antagonists,”)
Other drugs used to treat hypertension include
sympatholytic drugs (other than beta-adrenergic blockers), and vasodilators. At
times, a combination of drugs may be used.
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