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Chapter: Clinical Pharmacology: Cardiovascular drugs

Antihypertensive drugs

Antihypertensive drugs, which act to reduce blood pressure, areused to treat hypertension, a disorder characterized by elevation in systolic blood pressure, diastolic blood pressure, or both.

Antihypertensive drugs

Antihypertensive drugs, which act to reduce blood pressure, areused to treat hypertension, a disorder characterized by elevation in systolic blood pressure, diastolic blood pressure, or both.

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Treatment for hypertension typically begins with a thiazide diuret-ic or a calcium channel blocker. (For more information, see “Cal-cium channel blockers,”) The patient may also receive a beta-adrenergic antagonist, angiotensin-converting enzyme (ACE) inhibitor, or an angiotensin II receptor blocker. The choice of these drugs depends on whether the patient has a compelling indi-cation, such as heart failure, history of an MI, high risk of coro-nary artery disease (CAD), diabetes, or chronic kidney disease. (See “Beta-adrenergic antagonists,”)

 

Other drugs used to treat hypertension include sympatholytic drugs (other than beta-adrenergic blockers), and vasodilators. At times, a combination of drugs may be used. 

 

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Clinical Pharmacology: Cardiovascular drugs : Antihypertensive drugs |


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