Anticonvulsant drugs
Anticonvulsant drugs inhibit neuromuscular transmission and areprescribed for:
·
long-term management of
chronic epilepsy (recurrent seizures)
·
short-term management of
acute isolated seizures not caused by epilepsy, such as those occurring after
trauma or brain surgery.
·
In addition, some
anticonvulsants are used in the emergency treatment of status epilepticus (a
continuous seizure state).
·
Treatment of epilepsy
should begin with a single drug whose dosage is increased until seizures are
controlled or adverse reac-tions become problematic. Generally, a second
alternative should be tried as monotherapy before combination therapy is consid-ered. The choice of drug treatment
depends on seizure type, drug characteristics, and patient preferences.
Anticonvulsants fall into several major classes:
·
Hydantoins
·
barbiturates
·
iminostilbenes
·
benzodiazepines
·
carboxylic acid derivatives
·
1-(aminomethyl) cyclohexane–acetic acid
·
phenyltriazines
·
carboxamides
·
sulfamate-substituted monosaccharides
·
succinimides
·
sulphonamides
·
pyrrolidines.
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