What
non-anesthetic agents might the ophthalmolo-gist use to maximize surgical
outcome?
Intravenous agents, such as mannitol, dextran,
urea, as well as oral glycerol, will increase plasma osmotic pressure, decrease
aqueous humor formation, and reduce IOP (Table 43.2). Intravenous acetazolamide
will also lower IOP. Acetazolamide inhibits carbonic anhydrase and there-fore
interferes with the sodium pump responsible for aqueous humor formation.
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