Monitoring the Neuromuscular Junction

MONITORING THE NEUROMUSCULAR JUNCTION

Before purchasing a new nondepolarizing neuro-muscular blocker, your hospital requests an evaluation. You decide to measure the median effective dose, ED₅₀ (effective dose producing 50% twitch height depression) and ED₉₅ (effective dose producing 95% twitch height depression) in 100 patients using electromyography.