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Chapter: Pathology: Liver Pathology

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Liver Dysfunction

Dysfunction of the liver may be divided into 4 categories that may coexist:

LIVER DYSFUNCTION

 

Dysfunction of the liver may be divided into 4 categories that may coexist:

 

         Hepatic failure occurs in the setting of hepatic necrosis secondary to acute liver failure, chronic liver disease, and hepatocyte dysfunction.

 

         Portal hypertension occurs in the setting of cirrhosis or increased portal venous blood flow.

 

         Cholestasis occurs in the setting of impaired bile flow due to hepatocyte dysfunction or biliary obstruction.

 

         Cirrhosis occurs in the setting of hepatocyte injury and is usually an irrevers-ible nodular regeneration that is end stage.

 

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