INFLAMMATORY NEUROPATHY
Guillain-Barré syndrome is an
autoimmune disease leading to the destruction of Schwann cells and peripheral
nerve demyelination. Clinically, it is preceded by a viral illness. Muscular
weakness occurs with an ascending paralysis, accompanied by loss of deep tendon
reflexes. Diagnosis can be established with nerve conduction studies; lumbar
puncture shows elevated protein.
Microscopic examination
demonstrates inflammation and demyelination of periph-eral nerves and spinal
nerve roots, resulting in muscular weakness. Guillain-Barré syndrome is fatal
in 5% of cases because of respiratory paralysis. Treatment is plas-mapheresis
and immunoglobulin therapy.
Related Topics
Privacy Policy, Terms and Conditions, DMCA Policy and Compliant
Copyright © 2018-2023 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.