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Administration of Medicine in Nursing - Effects of Drug on Body | 12th Nursing : Chapter 9 : Administration of Medicine

Chapter: 12th Nursing : Chapter 9 : Administration of Medicine

Effects of Drug on Body

Here we come across with Pharmacokinetics and Pharmacodynamics of the drug.

EFFECTS OF DRUG ON BODY

Here we come across with Pharmacokinetics and Pharmacodynamics of the drug.

Pharmacokinetics – It describes the movement of the drug in our body, about its absorption, distribution, metabolism and excretion. 

Pharmacodynamics – It describes about the mechanism of action of a drug at cellular, sub-cellular, and at molecular levels. The important principles of mechanism of action are stimulation, depression, replacement, irritation and cytotoxic action.

 

Adverse Drug Effects

Side effects: are the unwanted but often unavoidable consequences of administered drug. E.g., aspirin produces gastric ulcer.

Toxic effects: they are due to over dosage or prolonged use. e.g., paracetamol causes hepatotoxicity..

Teratogenicity: it refers to the capacity of a drug to cause foetal abnormalities when administered to a pregnant mother. E.g., Tetracycline 

Idiosyncrasy: it is a genetically determined abnormal reaction to a drug in an unusual manner. E.g., barbiturates.

Drug dependence: drugs capable of altering mood and feelings on repeated use of such drugs. E.g., morphine

Iatrogenic disease: this a physician induced or drug induced disease. E.g., peptic ulcer by salicylates.

Drug allergy: it is an immunologically mediated unpredictable reactions which are not related to the therapeutic effects.

Carcinogenicity and Mutagenicity: it is the capacity of a drug to cause cancer. e.g., anabolic steroids.

 

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12th Nursing : Chapter 9 : Administration of Medicine : Effects of Drug on Body | Administration of Medicine in Nursing


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