ACUTE LEUKEMIAS
In acute leukemias, the
peripheral blood has decreased mature forms and increased immature forms called
blasts, which have immature
chromatin with nucleoli. The bone marrow has increased immature cells (blasts). Acute symptoms are second-ary to marrow failure,
which can produce decreased erythrocytes (causing anemia and fatigue),
decreased leukocytes (permitting infections and fever), and decreased platelets
(inducing bleeding).
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