LSD-Related Psychotic Disorders
Criteria for substance-induced psychotic disorders
are listed below in the DSM-IV-TR Criteria.
Among the hallucinogens, LSD has been associated
with the majority of, but not all, prolonged psychotic reactions follow-ing
acute drug use. Psychoses are apparently rare with the abuse of botanical
preparations, in all likelihood because such agents are of low potency, not
widely abused, and often controlled by religious sanctions. By comparison,
psychoses have been seen following the administration of LSD to patients and
experimental subjects. In addition to exhibiting positive signs of
schizophre-nia, patients with post-LSD psychoses show affective lability and
the novel addition of visual hallucinations uncommon in non-drug-related
psychoses. The uniqueness of post-LSD psychosis remains controversial. One
comparison of post-LSD psychosis and nondrug-related schizophrenia found no
essential clinical differences between the two (Vardy and Kay, 1983).