LSD-Related Psychotic Disorders

LSD-Related Psychotic Disorders

Criteria for substance-induced psychotic disorders are listed below in the DSM-IV-TR Criteria.

Among the hallucinogens, LSD has been associated with the majority of, but not all, prolonged psychotic reactions follow-ing acute drug use. Psychoses are apparently rare with the abuse of botanical preparations, in all likelihood because such agents are of low potency, not widely abused, and often controlled by religious sanctions. By comparison, psychoses have been seen following the administration of LSD to patients and experimental subjects. In addition to exhibiting positive signs of schizophre-nia, patients with post-LSD psychoses show affective lability and the novel addition of visual hallucinations uncommon in non-drug-related psychoses. The uniqueness of post-LSD psychosis remains controversial. One comparison of post-LSD psychosis and nondrug-related schizophrenia found no essential clinical differences between the two (Vardy and Kay, 1983).