What is
coronary steal and what agents might induce it?
Coronary steal may occur when a segment of the
myocardium distal to a stenotic coronary artery receives its major blood supply
from collateral vessels that originate from a “normal” segment of myocardium
supplied by a normal coronary artery. Arteriolar vasodilators (e.g.,
isoflu-rane, sodium nitroprusside, and dipyridamole) may decrease the flow
across the collateral vessels by dilating the arterioles in the normal segment
of myocardium. However, there is no convincing evidence that isoflurane should
be avoided in patients with CAD provided that excessive tachycardia and
hypotension do not occur. It would be prudent, though, to avoid arteriolar
vasodilators in patients with “steal-prone” anatomy.
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