Home | | Clinical Cases in Anesthesia | What are the treatment options for HOCM?

Chapter: Clinical Cases in Anesthesia : Hypertrophic Obstructive Cardiomyopathy

What are the treatment options for HOCM?

Medical therapy of HOCM is based on β-blockers (Table 8.1).

What are the treatment options for HOCM?

 

Medical therapy of HOCM is based on β-blockers (Table 8.1). Their beneficial effects are likely due to a depression of systolic function and an improvement in diastolic filling and relaxation. However, it is still not clear whether life expectancy is prolonged by this treatment. Amiodarone is a commonly used agent for the control of supraventricular and ventricular dysrhythmias.

 


Nonmedical treatment options are surgical myotomy/ myomectomy, percutaneous transluminal septal myo-cardial ablation, alcohol septal ablation, mitral valve replacement/valvuloplasty, or a combination of the former. The potential complications of surgical correction of the LVOT obstruction include complete heart block and late formation of a ventricular septal defect due to septal infarction.

 

Controlled studies did not confirm earlier reports that atrioventricular sequential (DDD) pacing is beneficial for patients with HOCM. Dual-chamber pacing can currently be recommended only in selected patients. The reported annual mortality rate is 1–3%, mostly due to ventricular dysrhythmias, sudden death, progressive heart failure, and atrial fibrillation with embolic stroke. There is accumulat-ing evidence that implantable automated defibrillator devices are highly effective in terminating malignant ventricular dysrhythmias in HOCM patients and, thus, decreasing the incidence of sudden death.

 

Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail
Clinical Cases in Anesthesia : Hypertrophic Obstructive Cardiomyopathy : What are the treatment options for HOCM? |


Privacy Policy, Terms and Conditions, DMCA Policy and Compliant

Copyright © 2018-2024 BrainKart.com; All Rights Reserved. Developed by Therithal info, Chennai.