Spinal Cord Transection and Spinal Shock
When the spinal cord is suddenly transected in the upper neck, at
first, essentially all cord functions, including the cord reflexes,
immediately become depressed to the point of total silence, a reaction called spinal shock. The reason for this is
that normal activity of the cord neurons depends to a great extent on continual
tonic excitation by the discharge of nerve fibers entering the cord from higher
centers, particularly discharge trans-mitted through the reticulospinal tracts,
vestibulospinal tracts, and corticospinal tracts.
After a few hours to a few weeks, the spinal neurons gradually
regain their excitability. This seems to be a natural characteristic of neurons
everywhere in the nervous system—that is, after they lose their source of
facilitatory impulses, they increase their own natural degree of excitability
to make up at least partially for the loss. In most nonprimates, excitability
of the cord centers returns essentially to normal within a few hours to a day
or so, but in human beings, the return is often delayed for several weeks and
occasionally is never complete; conversely, sometimes recovery is excessive,
with resultant hyperexcitability of some or all cord functions.
Some of the spinal functions specifically affected during or after
spinal shock are the following:
1. At onset of spinal
shock, the arterial blood pressure falls instantly and drastically—sometimes to
as low as 40 mm Hg—thus demonstrating that sympathetic nervous system activity
becomes blocked almost to extinction. The pressure ordinarily returns to normal
within a few days, even in human beings.
2. All skeletal muscle reflexes integrated in the spinal cord are
blocked during the initial stages of shock. In lower animals, a few hours to a
few days are required for these reflexes to return to normal; in human beings,
2 weeks to several months are sometimes required. In both animals and humans,
some reflexes may eventually become hyperexcitable, particularly if a few
facilitatory pathways remain intact between the brain and the cord while the
remainder of the spinal cord is transected. The first reflexes to return are
the stretch reflexes, followed in order by the progressively more complex
reflexes: flexor reflexes, postural antigravity reflexes, and remnants of
stepping reflexes.
3.The sacral reflexes for control of bladder and colon evacuation are suppressed in human beings for the first few weeks after cord transection, but in most cases they eventually return.
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