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Chapter: Basic & Clinical Pharmacology : Diuretic Agents

Renal Autacoids - Renal Tubule Transport Mechanisms

A number of locally produced compounds exhibit physiologic effects within the kidney and are therefore referred to as autacoids, or paracrine factors.

RENAL AUTACOIDS

A number of locally produced compounds exhibit physiologic effects within the kidney and are therefore referred to as autacoids, or paracrine factors. Several of these autacoids (adenosine, the prostaglandins, and urodilatin) appear to have important effects on the pharmacology of diuretics. Since these effects are complex, they will be treated independently of the individual tubule seg-ments discussed above.



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Basic & Clinical Pharmacology : Diuretic Agents : Renal Autacoids - Renal Tubule Transport Mechanisms |


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