RENAL AUTACOIDS
A
number of locally produced compounds exhibit physiologic effects within the
kidney and are therefore referred to as autacoids,
or paracrine factors. Several of
these autacoids (adenosine, the prostaglandins, and urodilatin) appear to have
important effects on the pharmacology of diuretics. Since these effects are
complex, they will be treated independently of the individual tubule seg-ments
discussed above.
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