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Chapter: Medicine Study Notes : Gastro-Intestinal

Other Malabsorption Syndromes

Tropical Sprue: Enterotoxic E coli infection in visitors to the tropics. Affects distal intestine

Other Malabsorption Syndromes

 

·        Lactose Intolerance:

 

o  Lactose intolerance very common: especially where diary products are uncommon. Either congenital (rare), acquired, or secondary to enteritis (i.e. be careful with milk for several weeks after bad diarrhoea)

 

o  Lactose breath test: Give lactose. Broken down by lactase. If ¯lactase then osmotic diarrhoea ® rapid transit ® early & large rise in H2 as lactose is broken down by bacteria. Check with serial breath H2 measurements


·        Tropical Sprue:  Enterotoxic E coli infection in visitors to the tropics.  Affects distal intestine

 

·        Whipple's Disease: Tropheryma whippelii (bacteria) infection. Obstruction to lymphatics causes malabsorption. Treat with erythromycin, otherwise death from systemic spread


·        Abetalipoproteinaemia: genetic defect, unable to synthesise apoproteins

 

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Medicine Study Notes : Gastro-Intestinal : Other Malabsorption Syndromes |


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