Gynecomastia is a unilateral or bilateral benign breast enlargement in a male. It is usually caused by an altered androgen-estrogen balance that favors estrogen effect. Microscopically, it is characterized by:
• Ductal epithelial hyperplasia
• Ductal elongation and branching
• Proliferation of periductal fibroblasts
• Increase in vascularity in the involved tissue
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