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Chapter: Medicine Study Notes : Genetics and Cancer

Epidemiology of Genetic Disorders and DNA - Genetics and Cancer

9,000 known genetic diseases, 5% have genetic diseases before 25.

Genetics and Cancer

Epidemiology of Genetic Disorders

 

·        9,000 known genetic diseases

·        5% have genetic diseases before 25

·        60% during lifetime (includes diabetes, heart disease, cancer)

 

DNA

 

·        There is frequent mutation in rapidly dividing cells: but repair mechanisms „mop up‟

·        If there is a sustained mutation in:

o   Essential gene ® lethal

o   Non-coding gene ® no effect 

o   Non-essential gene ® human variability/disease

 

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Medicine Study Notes : Genetics and Cancer : Epidemiology of Genetic Disorders and DNA - Genetics and Cancer |


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