Developmental Anomalies of the Lens
Anomalies of lens shape are very rare. Lenticonus is a circumscribed conical protrusion of the anterior pole
(anterior lenticonus) or posterior pole (poste-rior lenticonus). A
hemispherical protrusion is referred to as lentiglobus. Symptoms include myopia and reduced visual
acuity. Some patients with Alport’s syndrome (kidney disease accompanied by
sensorineural hearing loss and anomalies of lens shape) have anterior lenticonus. Posterior lenti-conus may be associated
with a lens opacity (Fig. 7.6). Treatment is the sameas for congenital or juvenile cataract.
Microphakia refers to a lens of abnormally small diameter. Any interrup-tion
of the development of the eye generally leads to microphakia. This can occur
for example in Weill-Marchesani syndrome (see Table 7.5).
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