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Chapter: Medicine Study Notes : Pharmacology

Bioavailability (F) - Pharmacokinetics

Fraction of drug that reaches the systemic circulation

Bioavailability (F)

 

·        = Fraction of drug that reaches the systemic circulation

·        F = AUC (Area under curve) after an oral dose/AUC after IV dose

·        Low F caused by poor absorption, or extensive metabolism in the gut wall or liver

 

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Medicine Study Notes : Pharmacology : Bioavailability (F) - Pharmacokinetics |


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