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Chapter: Clinical Pharmacology: Cardiovascular drugs

Antiarrhythmic drugs

Antiarrhythmic drugs are used to treat arrhythmias, disturbancesof the normal heart rhythm.

Antiarrhythmic drugs

Antiarrhythmic drugs are used to treat arrhythmias, disturbancesof the normal heart rhythm.Unfortunately, many antiarrhythmics are also capable of worsen-ing or causing the very arrhythmias they’re supposed to treat. The benefits need to be weighed carefully against the risks of antiar-rhythmic therapy.


A touch of class

 

Antiarrhythmics are categorized into four classes:

 

·                 I (which includes classes IA, IB, and IC)

 

·                 II

 

·                 III

 

·                 IV.

 

Class I antiarrhythmics consist of sodium channel blockers. This is the largest group of antiarrhythmics. Class I agents are fre-quently subdivided into classes IA, IB, and IC. One drug, adeno-sine (an AV nodal blocking agent used to treat paroxysmal supra-ventricular tachycardia), doesn’t fall into any of these classes.

 

The mechanisms of action of antiarrhythmics vary widely, and a few drugs exhibit properties common to more than one class.

 

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Clinical Pharmacology: Cardiovascular drugs : Antiarrhythmic drugs |


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